MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagy

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MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagy

Macropinocytosis, by which cells ingest large amounts of fluid, and autophagy, the lysosome-based catabolic process, involve vesicular biogenesis (early stage) and turnover (end stage). Much is known about early-stage events; however, our understanding of how the end stages of these processes are governed is incomplete. Here we demonstrate that the microRNA-103/107(miR-103/107) family, which is...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2016

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.201604032